Updated: February 6, 2026 Location: Morrisville, NC, United States Job ID: 25104754-OTHLOC-1500-2DNC-2DR Not ready to apply? Join our Talent Network Description Associate Director of Real World Evidence (Sponsor Dedicated/Remote-US) Syneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for. Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives. Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE Why Syneos Health • We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program. • We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people. • We are continuously building the company we all want to work for and our customers want to work with. Why? Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong. Job Responsibilities Associate Director, Real-World Evidence (Sponsor-Dedicated / Remote – US) Syneos Health is seeking an Associate Director of Real-World Evidence (RWE) to lead a Sponsor-dedicated team supporting high-impact evidence generation across the drug development lifecycle. This role combines scientific leadership, epidemiologic expertise, and people management, overseeing real-world data analytics, observational research, and late-phase evidence programs that inform regulatory, safety, and strategic decisions. This is a fully remote, US-based position offering the opportunity to shape how real-world insights are developed, delivered, and translated into meaningful outcomes for patients and Sponsors alike. What You Will Do: • Provide line management and leadership to a cross-functional RWE team, including staffing, performance management, coaching, and professional development • Serve as a scientific and technical leader for end-to-end RWE and observational studies, from study design through execution, analysis, and interpretation • Apply epidemiologic principles and real-world data methodologies to outcomes research, late-phase development, and regulatory-relevant use cases • Lead and coordinate cross-functional scientific teams, including epidemiologists, biostatisticians, data scientists, and analysts, within a matrixed, Sponsor-dedicated environment • Oversee delivery of global or multi-regional evidence generation programs, accounting for geographic considerations in data availability, regulatory expectations, and study design • Ensure high-quality, inspection-ready delivery of RWE workstreams, including adherence to timelines, standards, and Sponsor expectations • Support onboarding, training, and ongoing competency development of RWE staff • Partner closely with Sponsor stakeholders and internal functions to ensure alignment, clear communication, and timely issue escalation • Drive continuous improvement across RWE operations, including documentation, compliance, process rigor, and quality control Who You Are: (minimum requirements): • You are a trained epidemiologist or quantitative scientist who has evolved into a people leader and scientific strategist. You enjoy mentoring teams, setting scientific direction, and translating complex real-world data into credible, actionable evidence. • Formal training in epidemiology or a closely related quantitative discipline, with applied experience in real-world data research • Proven experience managing and developing scientific teams, with accountability for performance, quality, and delivery • Hands-on ownership of end-to-end RWE or observational studies, including use of secondary data sources such as claims, EHR, registries, or clinico-genomic data • Experience supporting late-phase and real-world evidence programs across multiple geographic regions • Comfortable working in matrixed, Sponsor-facing environments, influencing across functions without direct authority • Quality-focused, delivery-oriented, and adept at balancing scientific rigor with operational execution Preferred Background: The most competitive candidates typically bring: • An advanced degree in epidemiology, public health, biostatistics, data science, or a related scientific field • Experience in pharmaceutical, biotech, CRO, consulting, or Sponsor organizations supporting RWE, outcomes research, or observational studies • Strong understanding of real-world data sources and their application across clinical development, regulatory, safety, and commercial contexts • Prior experience in FSP or Sponsor-dedicated delivery models (nice to have) Why Join Syneos Health: At Syneos Health, you will work alongside talented scientific professionals at the forefront of real-world evidence generation. This role offers the opportunity to lead and grow a high-performing RWE team, influence how real-world insights support development and regulatory decisions, and make a meaningful impact on patient outcomes—while benefiting from a collaborative culture, strong leadership support, and long-term career growth! At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements. Salary Range: $114,000.00 - $210,900.00 The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. Get to know Syneos Health Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients. No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health. Additional Information Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job. Summary Management of RWE staff, responsibilities including administrative oversight, professional development, performance appraisals, and employee counselling for staff. May be involved in consulting of project work and will review workload for all direct reports. Manages staff by establishing goals that will increase knowledge and skill levels. Apply tot his job