[Remote] Sr. Principal Analyst, Statistical Programming

Note: The job is a remote job and is open to candidates in USA. Biogen is a mid-sized biotechnology company committed to excellence and innovation. The Senior Principal Analyst, Statistical Programming leads statistical programming activities, ensuring high-quality outputs and collaboration with various teams to meet project milestones.


Responsibilities

  • Leads, coordinates and manages timely creation, oversight, review, completion, and delivery of statistical programming activities and deliverables of study projects via internal and/or external staff oversight
  • Considered a statistical programming expert within the department. Authors CDISC ADaM (analysis data model) analysis data set specifications including the identification of potential data issues or areas of critical data examination. Works with statistics on defining and documenting programming endpoint algorithms across a study, drug program and/or contributing to TA level algorithms
  • Manage the end-to-end programming of deliverables through from CRF collections through electronic submission including preparation of electronic submissions (ESUB) components (input to reviewer’s guides, annotated CRF, define and XPTs), works with SMEs to ensure compliance to eSUB standards
  • Identifies process inefficiencies and lead efforts to remedy the inefficiencies and train the department on the new processes in conjunction with DVAD and PON
  • Serves as the Statistical Programming Lead to achieve milestones for a drug program; evaluates task objectives, collaborates with PL and/or manager on issues or resource needs
  • Verifies program consistency and usage of data, analysis and submission standards across the department in consultation with data standards, statistical submissions management and the data strategy plan
  • Informs internal and external project team members of statistical programming requirements, deliverable status, and resource needs

Skills

  • Bachelor's degree required
  • 10 years relevant work experience within an organization with a focus on data management and analysis
  • 10+ years SAS Base programming with 7+ years using SAS STAT, GRAPH and MACRO
  • 10+ years relevant industry experience
  • 10+ years clinical trial experience
  • 5+ years clinical database experience
  • CDISC and/or submissions experience
  • Extensive knowledge of drug development process and clinical trials
  • Extensive knowledge of drug submission requirements, relevant ICH and FDA/EMEA/ROW guidelines
  • Masters or PhD in Statistics or Mathematics
  • Familiarity with UNIX as well as software development packages (R, Imaging and Genomics software packages)
  • Familiarity AI and ML concepts

Benefits

  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation

Company Overview

  • Biogen is an American biotechnology company that provides therapeutics for neurological, autoimmune, and rare diseases. It was founded in 1978, and is headquartered in Cambridge, Massachusetts, USA, with a workforce of 5001-10000 employees. Its website is https://www.biogen.com/en_us/home.html.

  • Company H1B Sponsorship

  • Biogen has a track record of offering H1B sponsorships, with 100 in 2025, 93 in 2024, 101 in 2023, 134 in 2022, 104 in 2021, 114 in 2020. Please note that this does not guarantee sponsorship for this specific role.

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